Colorectal Cancer: Open Access

Bloodstream Infection due to Bacterial Co-Infection in Patients with Rectal Carcinoma: Report of Two Cases

In this study, we reported the bacterial co-infection causing bacteremia in two of 38 patients diagnosed with rectal carcinoma. 10 mL of blood of each patient were cultured in BHI broth. From positive blood cultures, aliquots were streaked on MacConkey agar (aerobiosis), and Bacteroides-bile-esculin agar and kanamycinblood agar (anaerobiosis). Bacteria were identified by using API-20A kit and confirmed by 16s rDNA sequencing. The bacterial identification showed the presence of Escherichia coli, Bacteroides fragilis and Enterococcus faecalis. The use of DNA sequencing showed to be a tool for rapid screening of blood infections than the classic microbiological methods, and provides an accurate and effective microbial identification in sepsis process. Patients with intestinal malignancy can produce bacteremia with nonspecific or atypical symptoms.

Author(s):

Rosa L Solis Castro, Gabriela G Freire Alberca, Claudia A Freire, Viviane Nakano, Luis A Llanco Albornoz, Adriana V Safatle Ribeiro, Ulysses R Junior and Mario J Avila-Campos

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