Colorectal Cancer: Open Access

Current Prevalence of HCV in Patients with Liver Disease and its Related Profile

Background: To study the prevalence of HCV in patients with Liver disease, HCV related patient’s profile, age, obesity, habits, biological marker, Co-morbidities, Diabetes, Obesity, Hepato Celluar Carcinoma (HCC) and detecting Liver stiffness.

Material and methods: Prevalence of HCV was studied in 69,353 patients with liver disease. Tests done and results were recorded.

Results: Overall prevalence of HCV in patients with liver disease was 1.3% in our present study, conducted in South Indian population. Statistical significance was found between screened patients and serological and virological reactive patients. Liner prevalence of HCV was observed and double fold increases in the year 2013. No bad habits were found in 49.7% and unhealthy habits in 50.3%. Co-morbidies found in 60.1% and no co- morbidies in 39.9%.

Prevalence of Diabetes mellitus and obese were 20.9% and 34.8% respectively in HCV reactive patients with liver disease. 2.5% of patients were with Hepato Cellular Carcinoma (HCC). Elevation of biological markers were studied (S. protein-63.9%, ALT -50.6%, AST-50.3%. Alkaline phosphatase-(M-35.5%, F-39.1%). As year progresses prevalence of HCV increased in both gender and HCV reactivity were higher in male than female. A statistical significant was found in detecting liver stiffness by fibroscan.

Conclusion: Liner increase of HCV was found. Higher numbers of patients were with unhealthy habits among the study population. CLD and CKD were found in higher percentage in HCV reactive patients with liver disease. 1/5 and 1/3 of our HCV reactive patients were Diabetic and obese respectively. Fibroscan was the best non-invasive marker in detecting liver stiffness in our study.

Author(s):

Narayanasamy K, Janifer Jasmine J, Jai Ganesh M, Senthil Kumar R, Koodal Raj A and Muthu Kumaran R

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